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Q.142 Botany ⭐ 360° Option Elimination Active
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NEET 2023 Botany Question 142 Solution

Topic: Principles of Inheritance and Variation · Official NTA Booklet Code G5
NEET 2023 Botany Question 142: Chromosomal Disorders: Klinefelter's Syndrome (47, XXY)

Question

Which of the following statements are correct about Klinefelter's Syndrome? A. This disorder was first described by Langdon Down (1866). B. Such an individual has overall masculine development. However, the feminine development is also expressed. C. The affected individual is short statured. D. Physical, psychomotor and mental development is retarded. E. Such individuals are sterile. Choose the correct answer from the options given below:

✓
Verified Against NTA Final Answer Key
Option (4) : B and E only
📚 Principles of Inheritance and Variation Easy
📋 Given Parameters & Problem Setup
Disorder Klinefelter's Syndrome
Karyotype 47, XXY (Aneuploidy due to extra X chromosome)
⚡

The 30-Second Exam Hall Shortcut: ⚡ Klinefelter's Syndrome Diagnostic: Masculine + Gynaecomastia + Sterile

⏱️ Save ~25 seconds

Down's syndrome was discovered by Langdon Down, has short stature and psychomotor retardation (ruling out A, C, D). Klinefelter's (47, XXY) features overall masculine development with feminine gynaecomastia (B) and sterility (E)! Select Option (4) B and E only!

1 Statement A: Discovered by Langdon Down -> False (Langdon Down described Down's syndrome).
2 Statement B: Overall masculine with feminine development expressed (gynaecomastia) -> True.
3 Statement C: Short statured -> False (Klinefelter individuals are typically tall; short stature describes Turner's or Down's).
4 Statement D: Psychomotor and mental development retarded -> False (Down's syndrome symptom).
5 Statement E: Individuals are sterile -> True.
6 B and E only -> Select Option (4).
🛡️
Why You Can 100% Trust This Shortcut: Canonical NCERT Genetics human chromosomal aneuploidy profiles.
📐

Step-by-Step Rigorous Workflow & Mathematical Proof

Step 1

Cytogenetics of Klinefelter's Syndrome

Klinefelter's syndrome is caused by the presence of an additional copy of the X-chromosome resulting in a 47, XXY47,\, XXY karyotype:

Karyotype: 44+XXY=47 Chromosomes  ⟹  Male phenotype with gynaecomastia\text{Karyotype: } 44 + XXY = \mathbf{47\text{ Chromosomes}} \implies \text{Male phenotype with gynaecomastia}
Step 2

Clinical Features in NCERT

Analyzing the canonical textbook descriptions: - "Such an individual has overall masculine development, however, the feminine development (development of breast, i.e., Gynaecomastia) is also expressed." (Statement B is TRUE) - "Such individuals are sterile." (Statement E is TRUE)

Step 3

Elimination of Down's Syndrome Traits

Statements A, C, and D describe Down's syndrome (trisomy 21): - First described by Langdon Down (1866) (Down's syndrome). - Short statured with small round head (Down's syndrome). - Physical, psychomotor, and mental development is retarded (Down's syndrome).

⭐

360° Option Elimination Engine Key Feature

Diagnose every choice: Know exactly why the right option works and why distractors fail.

4-Option Deep Scan
1 1
✗ Incorrect
Verdict & Scientific Reason:

Statement A describes Down's syndrome, not Klinefelter's.

⚠️
Student Fallacy (Why candidates pick this trap): Attributing the discovery of Klinefelter's syndrome to Langdon Down.
2 2
✗ Incorrect
Verdict & Scientific Reason:

Statement A is false.

⚠️
Student Fallacy (Why candidates pick this trap): Overlooking that Down's syndrome was described by Langdon Down.
3 3
✗ Incorrect
Verdict & Scientific Reason:

Statements C and D are classical diagnostic symptoms of Down's syndrome.

⚠️
Student Fallacy (Why candidates pick this trap): Confusing trisomy 21 symptoms with sex chromosomal trisomy.
4 4
✓ 100% Correct
Verdict & Scientific Reason:

Both B and E are true and specific features of Klinefelter's syndrome (47, XXY).

💡
Why this is airtight: None; precise syndrome distinction.
⚠️

NTA Trap Alert: Down's vs. Klinefelter's Symptom Cross-Contamination Trap

NTA blended symptoms of Down's syndrome (Langdon Down, short stature, psychomotor retardation) with Klinefelter's syndrome. Fast readers mistake all genetic disorder descriptions as interchangeable.

🛡️ How to avoid the -1 mark: Klinefelter's = Tall masculine stature + Gynaecomastia + Sterile. Down's = Langdon Down + Short stature + Furrowed tongue + Psychomotor retardation.
📖

Core NEET Syllabus Standard

NCERT Biology · Principles of Inheritance and Variation Standard Benchmark
Core Scientific Principle Tested:

"Klinefelter's syndrome individuals have overall masculine development, feminine breast development (gynaecomastia), and are sterile."

Syllabus Focus: Chromosomal Disorders (Klinefelter's Syndrome)
✓ Core NEET UG Syllabus Anchor Syllabus & Academic Standards ↗

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