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Q.194 Zoology ⭐ 360° Option Elimination Active
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NEET 2024 Zoology Question 194 Solution

Topic: Molecular Basis of Inheritance · Official NTA Booklet Code T1
NEET 2024 Zoology Question 194: Transcription Machinery: Polymerases, Promoters, Rho Factor, and Spliceosomes

Question

Match List I with List II. List I: A. RNA polymerase III; B. Termination of transcription; C. Splicing of Exons; D. TATA box. List II: I. snRNPs; II. Promotor; III. Rho factor; IV. SnRNAs, tRNA. Choose the correct answer from the options given below:

✓
Verified Against NTA Final Answer Key
Option (2) : A-IV, B-III, C-I, D-II
📚 Molecular Basis of Inheritance Medium
📋 Given Parameters & Problem Setup
List I (Transcriptional Elements) A: RNA polymerase III; B: Termination of transcription; C: Splicing of Exons; D: TATA box
List II (Molecules / Factors) I: snRNPs; II: Promotor; III: Rho factor; IV: SnRNAs, tRNA
⚡

The 30-Second Exam Hall Shortcut: ⚡ Eukaryotic Molecular Machinery Match

⏱️ Save ~25 seconds

RNA Pol III = tRNA and snRNAs (IV); Termination = Rho factor (III); Splicing = snRNPs / spliceosome (I); TATA box = Core promoter element (II)! Match: A-IV, B-III, C-I, D-II!

1 A. RNA polymerase III: Transcribes tRNA, 5S rRNA, and snRNAs (IV).
2 B. Termination of transcription: Mediated by termination factor Rho (ρ) in prokaryotes (III).
3 C. Splicing of Exons: Mediated by spliceosome complex containing snRNPs (snurps) (I).
4 D. TATA box: Gold-Hogness box located in the Promotor region of genes (II).
5 Matching order: A-IV, B-III, C-I, D-II -> Option (2) / B.
🛡️
Why You Can 100% Trust This Shortcut: NCERT Biology · Molecular Basis of Inheritance (Eukaryotic Transcription Machinery)
📐

Step-by-Step Rigorous Workflow & Mathematical Proof

Step 1

Match Eukaryotic RNA Polymerase Types

In eukaryotes, there are at least three RNA polymerases in the nucleus. RNA polymerase I transcribes rRNAs (28S, 18S, and 5.8S). RNA polymerase II transcribes precursor of mRNA (hnRNA). RNA polymerase III is responsible for transcription of tRNA, 5S rRNA, and snRNAs (small nuclear RNAs) (A -> IV).

Step 2

Match Termination, Splicing, and Promoters

- In bacteria, RNA polymerase associates transiently with termination factor (ρ\rho, rho factor) to terminate transcription (B -> III). - Splicing involves removal of introns and joining of exons, catalyzed by the spliceosome formed of small nuclear ribonucleoproteins (snRNPs) (C -> I). - The TATA box is a conserved hexanucleotide sequence found within the core promoter region of eukaryotic genes where transcription factors bind (D -> II).

Step 3

Confirm Sequence

A-IV, B-III, C-I, D-II corresponds to Option (2).

⭐

360° Option Elimination Engine Key Feature

Diagnose every choice: Know exactly why the right option works and why distractors fail.

4-Option Deep Scan
1 (1)
✗ Incorrect
Verdict & Scientific Reason:

Mismatches RNA polymerase III with Rho factor.

⚠️
Student Fallacy (Why candidates pick this trap): Mismatches RNA polymerase III with Rho factor.
2 (2)
✓ 100% Correct
Verdict & Scientific Reason:

Accurately pairs all transcriptional components and processing machinery with their molecular counterparts.

💡
Why this is airtight: None.
3 (3)
✗ Incorrect
Verdict & Scientific Reason:

Mismatches RNA polymerase III with promoter.

⚠️
Student Fallacy (Why candidates pick this trap): Mismatches RNA polymerase III with promoter.
4 (4)
✗ Incorrect
Verdict & Scientific Reason:

Mismatches RNA polymerase III with Rho factor.

⚠️
Student Fallacy (Why candidates pick this trap): Mismatches RNA polymerase III with Rho factor.
⚠️

NTA Trap Alert: RNA Pol I vs II vs III Substrates

Confusing products of RNA Polymerase II (hnRNA/mRNA) with RNA Polymerase III (tRNA, 5S rRNA, snRNA).

🛡️ How to avoid the -1 mark: Remember: Pol I = 28S, 18S, 5.8S rRNA; Pol II = hnRNA (mRNA); Pol III = tRNA, 5S rRNA, snRNA.
📖

Core NEET Syllabus Standard

Biology Core Zoology · Molecular Basis of Inheritance Standard Benchmark
Core Scientific Principle Tested:

"The RNA polymerase III is responsible for transcription of tRNA, 5srRNA, and snRNAs (small nuclear RNAs). The RNA polymerase associates transiently with termination-factor (rho) to terminate transcription. Splicing removes introns and joins exons."

Syllabus Focus: Transcription Machinery: Polymerases, Promoters, Rho Factor, and Spliceosomes
✓ Core NEET UG Syllabus Anchor Syllabus & Academic Standards ↗

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