Q.147 Botany ⭐ 360° Option Elimination Active

NEET 2024 Botany Question 147 Solution

Topic: Molecular Basis of Inheritance · Official NTA Booklet Code T1

Question

Match List I with List II. List I: A. Frederick Griffith; B. Francois Jacob & Jacque Monod; C. Har Gobind Khorana; D. Meselson & Stahl. List II: I. Genetic code; II. Semi-conservative mode of DNA replication; III. Transformation; IV. Lac operon. Choose the correct answer from the options given below:

✓

Verified Against NTA Final Answer Key

Option (4) : A-III, B-IV, C-I, D-II

📚 Molecular Basis of Inheritance Easy

📋 Given Parameters & Problem Setup

List I (Scientists) A: Frederick Griffith; B: Francois Jacob & Jacque Monod; C: Har Gobind Khorana; D: Meselson & Stahl

List II (Milestone Discoveries) I: Genetic code; II: Semi-conservative mode of DNA replication; III: Transformation; IV: Lac operon

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The 30-Second Exam Hall Shortcut: ⚡ Molecular Genetics Pioneers Match

⏱️ Save ~25 seconds

Griffith = Transformation in mice (III); Jacob & Monod = Lac operon (IV); Khorana = Genetic code synthesis (I); Meselson & Stahl = Semi-conservative DNA replication (II)! Match: A-III, B-IV, C-I, D-II!

1 A. Frederick Griffith (1928): Transforming principle in Streptococcus pneumoniae (III).

2 B. Francois Jacob & Jacques Monod (1961): First elucidated transcriptionally regulated system, the Lac operon (IV).

3 C. Har Gobind Khorana: Developed chemical method for synthesizing defined RNA homopolymers/copolymers to decipher Genetic code (I).

4 D. Meselson & Stahl (1958): Proved semi-conservative DNA replication using 15N in E. coli (II).

5 Matching order: A-III, B-IV, C-I, D-II -> Option (4) / D.

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Why You Can 100% Trust This Shortcut: NCERT Biology · Molecular Basis of Inheritance (Milestones in Molecular Genetics)

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Step-by-Step Rigorous Workflow & Mathematical Proof

Step 1

Match Transformation and Operon Model

Frederick Griffith conducted transformation experiments with Streptococcus pneumoniae, demonstrating transfer of genetic virulence (A -> III). Francois Jacob (geneticist) and Jacques Monod (biochemist) elucidated the lac operon mechanism in E. coli (B -> IV).

Step 2

Match Genetic Code and Semi-Conservative Replication

Har Gobind Khorana developed chemical synthesis of RNA molecules with defined combinations of bases to crack the genetic code (C -> I). Matthew Meselson and Franklin Stahl performed equilibrium density gradient centrifugation with heavy isotope 15N in E. coli, proving semi-conservative DNA replication (D -> II).

Step 3

Select Final Match

A-III, B-IV, C-I, D-II matches Option (4).

⭐

360° Option Elimination Engine Key Feature

Diagnose every choice: Know exactly why the right option works and why distractors fail.

4-Option Deep Scan

1 (1)

✗ Incorrect

Verdict & Scientific Reason:

Mismatches Griffith with Semi-conservative replication.

⚠️

Student Fallacy (Why candidates pick this trap): Mismatches Griffith with Semi-conservative replication.

2 (2)

✗ Incorrect

Verdict & Scientific Reason:

Mismatches Griffith with Lac operon.

⚠️

Student Fallacy (Why candidates pick this trap): Mismatches Griffith with Lac operon.

3 (3)

✗ Incorrect

Verdict & Scientific Reason:

Mismatches Jacob & Monod with Semi-conservative replication and Meselson & Stahl with Lac operon.

⚠️

Student Fallacy (Why candidates pick this trap): Mismatches Jacob & Monod with Semi-conservative replication and Meselson & Stahl with Lac operon.

4 (4)

✓ 100% Correct

Verdict & Scientific Reason:

Accurately pairs all four historic scientists with their celebrated molecular biology breakthroughs.

💡

Why this is airtight: None.

⚠️

NTA Trap Alert: Khorana vs Nirenberg

Wondering whether Nirenberg or Khorana cracked the genetic code.

🛡️ How to avoid the -1 mark: Both contributed jointly; Khorana synthesized defined RNA sequences while Nirenberg used cell-free translation systems.

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Core NEET Syllabus Standard

Biology Core Botany · Molecular Basis of Inheritance Standard Benchmark

Core Scientific Principle Tested:

"Frederick Griffith conducted transformation experiments... Francois Jacob and Jacques Monod elucidated the lac operon... Har Gobind Khorana developed chemical method for synthesis of RNA... Meselson and Stahl proved semi-conservative DNA replication."

Syllabus Focus: Historical Discoveries: Griffith, Jacob & Monod, Khorana, Meselson & Stahl

✓ Core NEET UG Syllabus Anchor Syllabus & Academic Standards ↗

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NEET 2024 Botany Question 147 Solution

Question

The 30-Second Exam Hall Shortcut: ⚡ Molecular Genetics Pioneers Match

Step-by-Step Rigorous Workflow & Mathematical Proof

Match Transformation and Operon Model

Match Genetic Code and Semi-Conservative Replication

Select Final Match

360° Option Elimination Engine Key Feature

NTA Trap Alert: Khorana vs Nirenberg

Core NEET Syllabus Standard

Ready to attempt under real exam pressure?

🔗 Related Questions — Molecular Basis of Inheritance

Lac Operon & Constitutive Expression of i-Gene

Eukaryotic RNA Polymerase II & hnRNA Synthesis

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Salient Features of the Human Genome

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