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Q.77 Zoology ⭐ 360° Option Elimination Active
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NEET 2020 Zoology Question 77 Solution

Topic: Molecular Basis of Inheritance · Official NTA Booklet Code E1
NEET 2020 Zoology Question 77: Watson-Crick Base Pairing Rules: Adenine Pairs with Thymine via Two H-Bonds

Question

Which of the following statements is correct?

  1. (1)Adenine pairs with thymine through two H-bonds.
  2. (2)Adenine pairs with thymine through one H-bond.
  3. (3)Adenine pairs with thymine through three H-bonds.
  4. (4)Adenine does not pair with thymine.
✓
Verified Against NTA Final Answer Key
Option (1) : Adenine pairs with thymine through two H-bonds.
📚 Molecular Basis of Inheritance Easy
📋 Given Parameters & Problem Setup
Molecular Structure Double-stranded B-DNA
Nitrogenous Base Pair Adenine (A) and Thymine (T)
Question Objective Identify the correct hydrogen bonding statement
⚡

The 30-Second Exam Hall Shortcut: ⚡ "A = T (Two H-Bonds); G ≡ C (Three H-Bonds)!"

⏱️ 20 seconds

According to Watson and Crick base-pairing rules, Adenine pairs with Thymine from the opposite strand through TWO hydrogen bonds (A=TA = T). Guanine pairs with Cytosine through THREE hydrogen bonds (G≡CG \equiv C). Statement (1) is 100% correct! Mark Option (1) in 5 seconds.

1 Watson-Crick double helix: Purine always pairs with pyrimidine.
2 Adenine (A) forms 2 hydrogen bonds with Thymine (T) (A=TA = T).
3 Guanine (G) forms 3 hydrogen bonds with Cytosine (C) (G≡CG \equiv C).
4 Statement 1 states: "Adenine pairs with thymine through two H-bonds."
5 Select Option (1).
🛡️
Why You Can 100% Trust This Shortcut: NCERT Biology · Molecular Basis of Inheritance (Structure of Polynucleotide Chain and Double Helix)
📐

Step-by-Step Rigorous Workflow & Mathematical Proof

Step 1

Watson-Crick Base Pairing Principle

In 1953, James Watson and Francis Crick proposed the double helix model for the structure of DNA based on X-ray diffraction data produced by Rosalind Franklin and Maurice Wilkins and Chargaff's base equivalence rules.

Step 2

Complementary Hydrogen Bonding Details

The two strands are held together by hydrogen bonds between nitrogenous bases: - Adenine forms TWO hydrogen bonds with Thymine (A=TA = T). - Guanine forms THREE hydrogen bonds with Cytosine (G≡CG \equiv C).

Step 3

Uniform Diameter of the Double Helix

Because a purine (two rings) always pairs with a pyrimidine (one ring), the distance between the two polynucleotide backbones remains constant at 2.0 nm throughout the length of the duplex.

Step 4

Evaluate the Four Statements

Statement (1) correctly states two H-bonds for A-T. Statements (2), (3), and (4) propose one, three, or no bonds, all of which are chemically erroneous.

⭐

360° Option Elimination Engine Key Feature

Diagnose every choice: Know exactly why the right option works and why distractors fail.

4-Option Deep Scan
1 A
✓ 100% Correct
Verdict & Scientific Reason:

Factually and chemically exact; Adenine and Thymine form two complementary hydrogen bonds in B-DNA.

💡
Why this is airtight: None; universally known cornerstone of molecular biology.
2 B
✗ Incorrect
Verdict & Scientific Reason:

Incorrect; one hydrogen bond is insufficient to stabilize base pairing.

⚠️
Student Fallacy (Why candidates pick this trap): Misremembering bond count.
3 C
✗ Incorrect
Verdict & Scientific Reason:

Incorrect; THREE hydrogen bonds exist between Guanine and Cytosine (G≡CG \equiv C), not Adenine and Thymine.

⚠️
Student Fallacy (Why candidates pick this trap): Confusing A-T pairing with G-C pairing.
4 D
✗ Incorrect
Verdict & Scientific Reason:

Incorrect; Adenine canonically pairs with Thymine in DNA.

⚠️
Student Fallacy (Why candidates pick this trap): Absurd distractor.
⚠️

NTA Trap Alert: A-T (2 bonds) vs G-C (3 bonds)

Never mix up the bond numbers: A-T has 2 H-bonds (lower melting temperature); G-C has 3 H-bonds (higher melting temperature).

🛡️ How to avoid the -1 mark: Mnemonic: "A-T = 2 letters = 2 bonds; G-C = 3 bonds"!
📖

Core NEET Syllabus Standard

Zoology · Molecular Basis of Inheritance Standard Benchmark
Core Scientific Principle Tested:

""

Syllabus Focus: Watson-Crick Base Pairing Rules: Adenine Pairs with Thymine via Two H-Bonds
✓ Core NEET UG Syllabus Anchor Syllabus & Academic Standards ↗

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