Q.136 Zoology ⭐ 360° Option Elimination Active

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NEET 2026 Zoology Question 136 Solution

Topic: Microbes in Human Welfare · Official NTA Booklet Code 50

Question

Which of the following is used as a clot buster?

(1)Streptokinase
(2)Penicillin
(3)Cyclosporin A
(4)Statins

✓

Verified Against NTA Final Answer Key

Option (1) : Streptokinase

📚 Microbes in Human Welfare Easy

📋 Given Parameters & Problem Setup

Therapeutic Function Clot Buster (Thrombolytic Agent)

Clinical Indication Emergency removal of intravascular clots in myocardial infarction

Given Options Streptokinase, Penicillin, Cyclosporin A, Statins

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The 30-Second Exam Hall Shortcut: ⚡ Bioactive Molecules Quad-Rule

⏱️ Save ~45 seconds

Streptokinase = Clot Buster; Cyclosporin A = Immunosuppressant; Statins = Cholesterol Lowering!

1 Recognize target clinical hallmark: "Clot buster" for clearing intravascular blood clots.

2 Recall: Streptokinase (produced by Streptococcus) is the medical clot buster.

3 Cyclosporin A (Trichoderma) is for organ transplant immunosuppression; Statins (Monascus) lower cholesterol.

4 Scan options: Option (1) is Streptokinase.

5 Pick Option (1) in under 5 seconds!

🛡️

Why You Can 100% Trust This Shortcut: NCERT Biology · Microbes in Human Welfare (Streptokinase produced by Streptococcus acts as a clot buster).

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Step-by-Step Rigorous Workflow & Mathematical Proof

Step 1

Microbial Source of Streptokinase

Streptokinase is an enzyme produced by the bacterium Streptococcus and modified by genetic engineering to improve its clinical efficacy and reduce allergic adverse reactions.

\text{Streptococcus (Bacterium)} \xrightarrow{\text{Genetic Engineering}} \text{Streptokinase (Enzyme)}

• Engineered for intravenous thrombolytic therapy.

Step 2

Physiological Mechanism as a Clot Buster

In the bloodstream, streptokinase binds to human plasminogen, activating it into active plasmin. Plasmin is a proteolytic enzyme that cleaves insoluble fibrin meshes holding intravascular thrombi together, dissolving the clot and reperfusing ischemic myocardium.

\text{Plasminogen} \xrightarrow{\text{Streptokinase}} \text{Plasmin} \xrightarrow{\text{Fibrinolysis}} \text{Dissolution of Blood Clot}

• Used clinically within the first few hours following acute myocardial infarction.

Step 3

Differentiate from Other Microbially Derived Agents

Penicillin is an antibiotic that inhibits bacterial peptidoglycan transpeptidation. Cyclosporin A is an immunosuppressive cyclic peptide from the fungus Trichoderma polysporum. Statins (from yeast Monascus purpureus) competitively inhibit HMG-CoA reductase to lower blood cholesterol.

\text{Clot Buster} \equiv \mathbf{Streptokinase} \implies \text{Option (1)}

• Matches official NTA final answer key Option A / (1).

⭐

360° Option Elimination Engine Key Feature

Diagnose every choice: Know exactly why the right option works and why distractors fail.

4-Option Deep Scan

1 A

✓ 100% Correct

Verdict & Scientific Reason:

100% accurate. Canonical microbial enzyme used as a clot buster in myocardial infarction.

💡

Why this is airtight: None; direct NCERT recall.

2 B

✗ Incorrect

Verdict & Scientific Reason:

Incorrect. Penicillin is an antibiotic derived from Penicillium notatum that kills bacteria, not a clot dissolver.

⚠️

Student Fallacy (Why candidates pick this trap): Confusing antimicrobial therapeutics with cardiovascular thrombolytics.

3 C

✗ Incorrect

Verdict & Scientific Reason:

Incorrect. Cyclosporin A is an immunosuppressant used in organ transplantation, not a clot buster.

⚠️

Student Fallacy (Why candidates pick this trap): Conflating different high-yield bioactive molecules from Table 10.1.

4 D

✗ Incorrect

Verdict & Scientific Reason:

Incorrect. Statins competitively inhibit HMG-CoA reductase to lower blood cholesterol, but do not dissolve acute fibrin clots.

⚠️

Student Fallacy (Why candidates pick this trap): Confusing long-term cholesterol reduction with emergency thrombolysis.

⚠️

NTA Trap Alert: Confusing Streptokinase with Statins

Both relate to cardiovascular therapy, leading students to confuse statins (cholesterol-lowering agents) with streptokinase (acute clot-busting enzymes).

🛡️ How to avoid the -1 mark: Remember: Streptokinase KILLS the clot; Statins SLOW cholesterol synthesis.

📖

Core NEET Syllabus Standard

NEET Biology Core Syllabus · Microbes in Human Welfare Standard Benchmark

Core Scientific Principle Tested:

"Streptokinase produced by Streptococcus functions as a clot buster for removing clots from blood vessels of patients suffering from myocardial infarction."

Syllabus Focus: Chemicals, Enzymes and other Bioactive Molecules

✓ Core NEET UG Syllabus Anchor Syllabus & Academic Standards ↗

Strepto-Kinase Kills the Clot; Monascus-Statin Stops Cholesterol on the spot!

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NEET 2026 Zoology Question 136 Solution

Question

The 30-Second Exam Hall Shortcut: ⚡ Bioactive Molecules Quad-Rule

Step-by-Step Rigorous Workflow & Mathematical Proof

Microbial Source of Streptokinase

Physiological Mechanism as a Clot Buster

Differentiate from Other Microbially Derived Agents

360° Option Elimination Engine Key Feature

NTA Trap Alert: Confusing Streptokinase with Statins

Core NEET Syllabus Standard

Ready to attempt under real exam pressure?

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