📋 Given Parameters & Problem Setup
List-I A. Alfred Hershey and Martha Chase, B. Euchromatin, C. Frederick Griffith, D. Heterochromatin
List-II I. Streptococcus pneumoniae, II. Densely packed and dark-stained, III. Loosely packed and light-stained, IV. DNA as genetic material confirmation
Hershey-Chase = DNA confirmation using ³²P/³⁵S (IV); Euchromatin = Loosely packed, light-stained, active (III); Griffith = Transformation in Streptococcus pneumoniae (I); Heterochromatin = Densely packed, dark-stained, inactive (II)!
1 Match each scientist and chromatin structure instantly:
2 - Alfred Hershey and Martha Chase (1952): Unequivocal confirmation that DNA is the genetic material using bacteriophage T2 (A -> IV).
3 - Euchromatin: Loosely coiled region of chromatin, stains light, transcriptionally active (B -> III).
4 - Frederick Griffith (1928): Transformation experiments with Streptococcus pneumoniae (Diplococcus) in mice (C -> I).
5 - Heterochromatin: Densely packed chromatin, stains dark, transcriptionally inactive (D -> II).
6 Combined code: A-IV, B-III, C-I, D-II -> Option (3)!
7 Solved in under 10 seconds!
🛡️ Why You Can 100% Trust This Shortcut: DNA Replication Machinery & Okazaki Fragments (NCERT Biology · Molecular Basis of Inheritance: DNA polymerase continuous vs discontinuous synthesis).
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A frequent stumbling block: EUchromatin is "TRUE" chromatin -> loose, light-staining, transcriptionally active. HETEROchromatin is densely packed, dark-staining, transcriptionally silent.
🛡️ How to avoid the -1 mark: Eu = "Good/Active" (Loose & Light); Hetero = "Heavy" (Dense & Dark).
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NEET Biology Core Syllabus · Molecular Basis of Inheritance Standard Benchmark
Core Scientific Principle Tested:
"Hershey-Chase proved DNA is the genetic material; Griffith used Streptococcus; euchromatin is light/loose, and heterochromatin is dark/dense."
Syllabus Focus: The Genetic Material & Packaging of DNA Helix
H-C confirms DNA (IV), Griffith did Strep (I), Eu is Light (III), Hetero is Dark (II)!
