NEET 2020 Zoology Question 59 Solution
Question
The enzyme enterokinase helps in conversion of:
- (1)protein into polypeptides
- (2)trypsinogen into trypsin
- (3)caseinogen into casein
- (4)pepsinogen into pepsin
Dynamic 180-question full-length simulator mixed dynamically from all 6 years for 2027 & 2026 aspirants.
The enzyme enterokinase helps in conversion of:
Enterokinase is secreted by the intestinal mucosa and specifically converts inactive pancreatic trypsinogen into active trypsin. Active trypsin then autocatalytically activates all other pancreatic zymogens (chymotrypsinogen, procarboxypeptidase). Mark Option (2) in 5 seconds!
Enterokinase (also called enteropeptidase) is a brush-border proteolytic enzyme secreted by the duodenal intestinal mucosa.
Pancreatic juice contains inactive zymogens: trypsinogen, chymotrypsinogen, procarboxypeptidases, amylases, lipases, and nucleases. Enterokinase specifically cleaves a hexapeptide from inactive trypsinogen to convert it into active trypsin.
Once activated, trypsin acts as the master activator that proteolytically cleaves and activates the other inactive enzymes in the pancreatic juice (chymotrypsinogen into chymotrypsin, procarboxypeptidase into carboxypeptidase).
Pepsinogen is converted into pepsin by gastric HCl (not enterokinase); caseinogen to casein involves rennin/pepsin. Thus, enterokinase uniquely activates trypsinogen into trypsin.
Diagnose every choice: Know exactly why the right option works and why distractors fail.
Incorrect; the breakdown of proteins into polypeptides is catalyzed by pepsin, trypsin, and chymotrypsin, not by enterokinase directly.
Factually exact; enterokinase cleaves the N-terminal inhibitory peptide from trypsinogen to yield active trypsin.
Incorrect; curdling of milk protein involves rennin (in infants) or pepsin and calcium ions, not enterokinase.
Incorrect; pepsinogen is activated into pepsin by hydrochloric acid (HCl) in gastric juice, not by enterokinase.
Gastric: Pepsinogen -> Pepsin (by HCl). Pancreatic: Trypsinogen -> Trypsin (by Intestinal Enterokinase).
""
Test your speed and accuracy in the authentic 180-minute timed NTA simulator.
Spotted a mistake in this solution? Report an error (support@mycompetitiveexams.com)
Cover all 1,140 official NEET questions in 285 days at your own pace. Progress is saved on your device. No login needed.